Publications

Eyal Raz

de Jong PR, Taniguchi K, Harris AR, Bertin S, Takahashi N, Duong J, Campos AD, Powis G, Corr M, Karin M, Raz E.ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation. Nat Commun. 2016 May 17;7: 11551. doi: 10.1038/ncomms11551. PubMed PMID: 27187615; PubMed Central PMCID: PMC4873670.

Bertin S, Aoki-Nonaka Y, de Jong PR, Nohara LL, Xu H, Stanwood SR, Srikanth S, Lee J, To K, Abramson L, Yu T, Han T, Touma R, Li X, González-Navajas JM, Herdman S, Corr M, Fu G, Dong H, Gwack Y, Franco A, Jefferies WA, Raz E.The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4⁺ T cells. Nat Immunol. 2014 Nov;15(11):1055-1063. doi: 10.1038/ni.3009. Epub 2014 Oct 5. PubMed PMID: 25282159; PubMed Central PMCID: PMC4843825.

de Jong PR, Takahashi N, Peiris M, Bertin S, Lee J, Gareau MG, Paniagua A, Harris AR, Herdman DS, Corr M, Blackshaw LA, Raz E.TRPM8 on mucosal sensory nerves regulates colitogenic responses by innate immune cells via CGRP. Mucosal Immunol. 2015 May;8(3):491-504. doi: 10.1038/mi.2014.82. Epub 2014 Oct 1. PubMed PMID: 25269705; PubMed Central PMCID: PMC4382463.

de Jong PR, Takahashi N, Harris AR, Lee J, Bertin S, Jeffries J, Jung M, Duong J, Triano AI, Lee J, Niv Y, Herdman DS, Taniguchi K, Kim CW, Dong H, Eckmann L, Stanford SM, Bottini N, Corr M, Raz E.Ion channel TRPV1-dependent activation of PTP1B suppresses EGFR-associated intestinal tumorigenesis. J Clin Invest. 2014 Sep;124(9):3793-806. doi: 10.1172/JCI72340. Epub 2014 Aug 1. PubMed PMID: 25083990; PubMed Central PMCID: PMC4151223.

Photo: Immunofluorescence photomicrograph demonstrating the intestinal niche of Nippostrongylus brasiliensis, a hookworm that colonizes the mouse gut and is used to model gastrointestinal nematode infections in humans. Photo Credit: Herbert laboratory, University of Pennsylvania School of Veterinary Medicine.