Mitchell Kronenberg

Wang S, Ljubimov AV, Jin L, Pfeffer K, Kronenberg M, Ghiasi H. Herpes Simplex Virus 1 Latency and the Kinetics of Reactivation Are Regulated by a Complex Network of Interactions between the Herpesvirus Entry Mediator, Its Ligands (gD, BTLA, LIGHT, and CD160), and the Latency-Associated Transcript. J Virol. 2018 Nov 27;92(24). pii: e01451-18. doi: 10.1128/JVI.01451-18. PubMed PMID: 30282707.

Seo GY, Shui JW, Takahashi D, Song C, Wang Q, Kim K, Mikulski Z, Chandra S, Giles DA, Zahner S, Kim PH, Cheroutre H, Colonna M, Kronenberg M. LIGHT-HVEM Signaling in Innate Lymphoid Cell Subsets Protects Against Enteric Bacterial Infection. Cell Host Microbe. 2018 Aug 8;24(2):249-260.e4. doi: 10.1016/j.chom.2018.07.008. PubMed PMID: 30092201; PubMed Central PMCID: PMC6132068.

Hartmann N, Kronenberg M. Cancer immunity thwarted by the microbiome. Science. 2018 May 25;360(6391):858-859. doi: 10.1126/science.aat8289. PubMed PMID: 29798871.

Herro R, Shui JW, Zahner S, Sidler D, Kawakami Y, Kawakami T, Tamada K, Kronenberg M, Croft M. LIGHT-HVEM signaling in keratinocytes controls development of dermatitis. J Exp Med. 2018 Feb 5;215(2):415-422. doi: 10.1084/jem.20170536. PubMed PMID: 29339444; PubMed Central PMCID: PMC5789407.

Edwards RG, Kopp SJ, Ifergan I, Shui JW, Kronenberg M, Miller SD, Longnecker R. Murine Corneal Inflammation and Nerve Damage After Infection With HSV-1 Are Promoted by HVEM and Ameliorated by Immune-Modifying Nanoparticle Therapy. Ophthalmol Vis Sci. 2017 Jan 1;58(1):282-291. doi: 10.1167/iovs.16-20668. PubMed PMID: 28114589; PubMed Central PMCID: PMC5256684.

Sibilano R, Gaudenzio N, DeGorter MK, Reber LL, Hernandez JD, Starkl PM, Zurek OW, Tsai M, Zahner S, Montgomery SB, Roers A, Kronenberg M, Yu M, Galli SJ. A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice. Nat Commun. 2016 Dec 16;7: 13696. doi: 10.1038/ncomms13696. PubMed PMID: 27982078; PubMed Central PMCID: PMC5171877.

Krause P, Zahner SP, Kim G, Shaikh RB, Steinberg MW, Kronenberg M. The tumor necrosis factor family member TNFSF14 (LIGHT) is required for resolution of intestinal inflammation in mice. Gastroenterology. 2014 Jun;146(7):1752-62.e4. doi: 10.1053/j.gastro.2014.02.010. Epub 2014 Feb 19. PubMed PMID: 24560868; PubMed Central PMCID: PMC4035425.

Steinberg MW, Huang Y, Wang-Zhu Y, Ware CF, Cheroutre H, Kronenberg M. BTLA interaction with HVEM expressed on CD8(+) T cells promotes survival and memory generation in response to a bacterial infection. PLoS One. 2013 Oct 30;8(10): e77992. doi: 10.1371/journal.pone.0077992. eCollection 2013. PubMed PMID: 24205057; PubMed Central PMCID: PMC3813523.

Shui JW, Larange A, Kim G, Vela JL, Zahner S, Cheroutre H, Kronenberg M. HVEM signaling at mucosal barriers provides host defence against pathogenic bacteria. Nature. 2012 Aug 9;488(7410):222-5. doi: 10.1038/nature11242. PubMed PMID: 22801499; PubMed Central PMCID: PMC3477500.

Steinberg MW, Turovskaya O, Shaikh RB, Kim G, McCole DF, Pfeffer K, Murphy KM, Ware CF, Kronenberg M. A crucial role for HVEM and BTLA in preventing intestinal inflammation. J Exp Med. 2008 Jun 9;205(6):1463-76. doi: 10.1084/jem.20071160. Epub 2008 Jun 2. PubMed PMID: 18519647; PubMed Central PMCID: PMC2413041.

Photo: Immunofluorescence photomicrograph demonstrating the intestinal niche of Nippostrongylus brasiliensis, a hookworm that colonizes the mouse gut and is used to model gastrointestinal nematode infections in humans. Photo Credit: Herbert laboratory, University of Pennsylvania School of Veterinary Medicine.