Past Grant Recipients

2013 Grant Recipients

Translational Pilots:

Title	PI	Institution
To characterize the dynamics and function of Flu-specific T cells induced by different lung DC subsets in human lungs	Miriam Merad	Mt. Sinai School of Medicine
Prevalence and Phenotype of Human Lung Resident MAIT Cells in Infectious and Non-Infectious Pulmonary Infection	David Lewinsohn	Oregon Health & Science University
The relationship of MR1 and MAIT cells to inflammatory bowel disease	Marielle Gold	Oregon Health & Science University
Molecular mechanism underlying tolerogenic vs. immunogenic intestinal DCs	Mary Jo Wick	Goetborg University
Innate Immunity in Chronic Airway Disease	Michael Holtzman	Washington University
IBD-associated PRDM-1 polymorphisms and CD4+ T cell function in Intestinal mucosa	Gislaine Martins	Cedars Sinai
Influence of gene-environment interactions on innate immune function of human Paneth cells	Thaddeus Stappenbeck	Washington University
Mucosal immune mechanisms that impact urinary tract infection outcome	Scott Hultgren	Washington University

Young Investigator Pilots:

Title	PI	Institution
Innate Lymphoid cell regulation of adaptive immunity and intestinal homeostasis	Gregory Sonnenberg	University of Pennsylvania
Regulation of Maternal-Fetal Mucosal Immunity by HEXIM1 and Extrathymic AIRE	Kang Chen	Wayne State University
Vanilloid Receptor 1 regulates gut-pancreas immunological axis	Sreyashi Basu	University of Connecticut Health Center
IDO1 in the gut epithelium	Matthew Ciorba	Washington University
Early Mucosal B cell development	Duane Wesemann	Brigham and Women's Hospital
Molecular regulation of colonic mucus, an innate defense barrier	Malin Johansson	University of Goethenburg
The role of bladder macrophages in determining susceptibility to cystitis	Thomas Hannan	Washington University

2012 Grant Recipients

Pilot Projects:

Title	PI	Institution
The role of mucins in antigen discovery and immune homeostasis	Rodney Newberry Mark Miller Gunnar Hansson Andrea Cerutti	Washington University Washington University Goetborg University Mt. Sinai School of Medicine
Requirements for development and function of mucosal TCR gd T cells	Leo Lefrancois David Artis John Wherry	University of Connecticut University of Pennsylvania University of Pennsylvania
Visualizing early virus-host interactions during enteric MNV infection	David Artis John Wherry Rodney Newberry Mark Miller	University of Pennsylvania University of Pennsylvania Washington University Washington University
Transepithelial delivery of inhaled antigens	Rodney Newberry Mark Miller Miriam Merad	Washington University Washington University Mt. Sinai School of Medicine
Influence of gut commensals and pathogenic bacteria on lung immunity to flu	Miriam Merad David Artis John Wherry	Mt. Sinai School of Medicine University of Pennsylvania University of Pennsylvania
The Role of Mucus in Bladder Defense Against Bacterial Uropathogens	Thomas Hannan Gunnar Hansson	Washington University Goetborg University

Core Resources:

Title	PI	Institution
Marco Colonna	Washington University	MIST core facility for generation of reporter and knockout mice to study mucosal immunity
Mark Miller	Washington University	MIST: Mucosal immunity studies two-photon imaging web resources and training

Learn more:

Pilot Project Overview
Application Instructions
Current Grant Recipients
Frequently Asked Questions

Photo: Color enhanced histologic image showing intestinal tissue damage in a murine model of intestinal inflammation. Photo Credit: Artis and Sonnenberg laboratories, Weill Cornell Medical College.